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RIVM

To

Ministry of Agriculture, Mrs A. Burger,

Ministry of Public Health, Mr P.H. Huyts

Subject

Advice for culling policy and killing methods of goats infected with Q-fever.

Date

15 December 2009

Dear Mrs Burger, dear Mr Huyts,

On Friday afternoon I received your request for advice regarding the various options of killing methods

for pregnant goats and sheep at infected farms. During the meeting on 14 December four other questions

were laid down before the experts.

Two of those questions were elaborately answered in the letter from the CVI (Mr Bianchi) to the CVO

(Ms Bruschke). The other experts whom we consulted support the advice of the CVI. We have attached

the CVI report.

The other questions I have put before veterinary experts and an ‘arbo’ (= employment) expert.

The experts emphasise that the advices regarding the killing methods are focused on limiting the

dispersion of C. burnetii from infected animals by minimising the number of handling the animals and

limiting the locations where animals are taken to. It is important to keep the risk for employees as low as

possible.

I will give you the substantiations and answers point by point.

Question 1.

Concerning non-vaccinated farms with positive bulk milk test.

What effect can we expect from vaccinating pregnant animals?

Considerations

There are no reliable data available. Part of these animals will already be infected, even when the test is

not (yet) positive. In such cases vaccination does not reduce the spreading of Coxiella burnetii. A

number of these animals will not yet be infected. There is doubt about the effect of vaccination of

pregnant animals, but also a lack of useful data regarding goats.

Advice

The experts believe that vaccination of pregnant animals does not result in the desired effect on

excretion of C. burnetii. See further comment and substantiation given by the CVI.

Question 2.

Concerning vaccinated farms with positive bulk milk test.

Would it be possible to make a distinction between high and low contamination farms?